Klain’s past experience focused on U.S. domestic politics. His view on China has not been made public over the years. In addition, Klain’s role as White House Chief of Staff does not have direct influence on the China policy of the Biden administration. However, as a coordinator who manages relations between Biden’s Cabinet members, Klain will play an important administrative role in coordinating foreign policy personnel who are reported to have various agenda and priorities regarding the administration’s China policy, which potentially rivals each other. 

As White House Chief of Staff, Klain oversaw daily press releases, including statements related to the administration’s China policies. How Klain manages the messages put out by the administration on social media and press conferences would influence the development of the U.S.-China relationship, which deteriorated partially due to a “war of words” during the Trump era. Furthermore, as the COVID-19 pandemic remains the primary focus of the Biden administration, Klain may provide his expertise  from his experience as the White House Ebola Response Coordinator in dealing with the pandemic, which would have significant implications to the economy and U.S. relations with China.